High-throughput, image-based screening of pooled genetic variant libraries

Image-based, high-throughput screening of genetic perturbations will advance both biology and biotechnology. We report a high-throughput screening method that allows diverse genotypes and corresponding phenotypes to be imaged in numerous individual cells. We achieve genotyping by introducing barcode...

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Detalles Bibliográficos
Autores principales: Emanuel, George, Moffitt, Jeffrey R., Zhuang, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958624/
https://www.ncbi.nlm.nih.gov/pubmed/29083401
http://dx.doi.org/10.1038/nmeth.4495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958624/
https://www.ncbi.nlm.nih.gov/pubmed/29083401
http://dx.doi.org/10.1038/nmeth.4495

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