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High-throughput, image-based screening of pooled genetic variant libraries
Image-based, high-throughput screening of genetic perturbations will advance both biology and biotechnology. We report a high-throughput screening method that allows diverse genotypes and corresponding phenotypes to be imaged in numerous individual cells. We achieve genotyping by introducing barcode...
Autores principales: | Emanuel, George, Moffitt, Jeffrey R., Zhuang, Xiaowei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958624/ https://www.ncbi.nlm.nih.gov/pubmed/29083401 http://dx.doi.org/10.1038/nmeth.4495 |
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