Inhibition of DNA methyltransferase 1 by RNA interference reverses epithelial-mesenchymal transition in highly metastatic 95D lung cancer cells by inhibiting the Wnt signaling pathway

Epigenetic modifications serve important roles in non-small cell lung cancer (NSCLC) tumorigenesis; however, the role of DNA methyltransferase 1 (DNMT1) in lung cancer progression remains unclear. In the present study, the expression of DNMT1 in the human NSCLC cell lines 95D (high invasive ability)...

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Detalles Bibliográficos
Autores principales: Bu, Xiancong, Zhang, Xiangyan, Xu, Jinhong, Yang, Heping, Zhou, Xiangdong, Wang, Haijing, Gong, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958636/
https://www.ncbi.nlm.nih.gov/pubmed/29805653
http://dx.doi.org/10.3892/ol.2018.8449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958636/
https://www.ncbi.nlm.nih.gov/pubmed/29805653
http://dx.doi.org/10.3892/ol.2018.8449

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