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Effects of valproic acid on the susceptibility of human glioma stem cells for TMZ and ACNU

To investigate the effect of valproic acid (VPA) on the susceptibility of glioma stem cells to temozolomide (TMZ) and nimustine (ACNU), the O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and its expression of MGMT were examined. A total of 3 glioma cell populations were isolated...

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Detalles Bibliográficos
Autores principales: Li, Zhiying, Xia, Yun, Bu, Xingyao, Yang, Dongyi, Yuan, Yiqiang, Guo, Xiaohe, Zhang, Gangzhong, Wang, Zhanwei, Jiao, Jichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958707/
https://www.ncbi.nlm.nih.gov/pubmed/29805689
http://dx.doi.org/10.3892/ol.2018.8551