Cargando…

Effects of valproic acid on the susceptibility of human glioma stem cells for TMZ and ACNU

To investigate the effect of valproic acid (VPA) on the susceptibility of glioma stem cells to temozolomide (TMZ) and nimustine (ACNU), the O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and its expression of MGMT were examined. A total of 3 glioma cell populations were isolated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zhiying, Xia, Yun, Bu, Xingyao, Yang, Dongyi, Yuan, Yiqiang, Guo, Xiaohe, Zhang, Gangzhong, Wang, Zhanwei, Jiao, Jichao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958707/ https://www.ncbi.nlm.nih.gov/pubmed/29805689 http://dx.doi.org/10.3892/ol.2018.8551

Ejemplares similares

FANCD1/BRCA2 Plays Predominant Role in the Repair of DNA Damage Induced by ACNU or TMZ
por: Kondo, Natsuko, et al.
Publicado: (2011)

Correction: FANCD1/BRCA2 Plays Predominant Role in the Repair of DNA Damage Induced by ACNU or TMZ
por: Kondo, Natsuko, et al.
Publicado: (2011)

Enhanced effect of reserpine upon growth-inhibitory action of ACNU on ACNU-resistant C6 glioma.
por: Yoshida, T., et al.
Publicado: (1986)

Intrathecal chemotherapy with ACNU for meningeal gliomatosis.
por: Yoshida, T. K., et al.
Publicado: (1992)

Phase I trial of convection-enhanced delivery of nimustine hydrochloride (ACNU) for brainstem recurrent glioma
por: Saito, Ryuta, et al.
Publicado: (2020)

DDEL-08. CONVECTION-ENHANCED DELIVERY OF NIMUSTINE HYDROCHLORIDE (ACNU) AGAINST PEDIATRIC DIFFUSE INTRINSIC PONTINE GLIOMAS
por: Saito, Ryuta, et al.
Publicado: (2020)

Radiosensitization of Glioma Cells by Temozolomide (TMZ): A Colony Formation Assay
por: Babaloui, Somayyeh, et al.
Publicado: (2022)

Self-assembled angiopep-2 modified lipid-poly (hypoxic radiosensitized polyprodrug) nanoparticles delivery TMZ for glioma synergistic TMZ and RT therapy
por: Zong, Zhenkun, et al.
Publicado: (2019)

Mild thermotherapy and hyperbaric oxygen enhance sensitivity of TMZ/PSi nanoparticles via decreasing the stemness in glioma
por: Zeng, Xiaofan, et al.
Publicado: (2019)

Phase 1 study of temozolamide (TMZ) combined with procarbazine (PCB) in patients with gliomas
por: Newlands, E S, et al.
Publicado: (2003)

TOPK inhibits autophagy by phosphorylating ULK1 and promotes glioma resistance to TMZ
por: Lu, Hui, et al.
Publicado: (2019)

Antitumor effects of ribavirin in combination with TMZ and IFN-β in malignant glioma cells
por: Ochiai, Yushi, et al.
Publicado: (2020)

Experimental study of selective MGMT peptides mimicking TMZ drug resistance in glioma
por: Wu, Yue, et al.
Publicado: (2022)

A novel series of phenolic temozolomide (TMZ) esters with 4 to 5-fold increased potency, compared to TMZ, against glioma cells irrespective of MGMT expression
por: Shervington, Leroy, et al.
Publicado: (2020)

Valproic Acid Inhibits Glioma and Its Mechanisms
por: Yang, Zhao-Yu, et al.
Publicado: (2022)

The Interleukin-33/ST2 axis promotes glioma mesenchymal transition, stemness and TMZ resistance via JNK activation
por: Lin, Lin, et al.
Publicado: (2020)

OKN-007 Increases temozolomide (TMZ) Sensitivity and Suppresses TMZ-Resistant Glioblastoma (GBM) Tumor Growth()()
por: Towner, Rheal A., et al.
Publicado: (2018)

Role of Metformin and AKT Axis Modulation in the Reversion of Hypoxia Induced TMZ-Resistance in Glioma Cells
por: Lo Dico, Alessia, et al.
Publicado: (2019)

Molecular dissection of the valproic acid effects on glioma cells
por: Hoja, Sabine, et al.
Publicado: (2016)

TRPC5 mediates TMZ resistance in TMZ-resistant glioblastoma cells via NFATc3-P-gp pathway
por: Zou, Yan, et al.
Publicado: (2021)

LOXL2 Upregulation in Gliomas Drives Tumorigenicity by Activating Autophagy to Promote TMZ Resistance and Trigger EMT
por: Zhang, Qing, et al.
Publicado: (2020)

Hispidulin Enhances Temozolomide (TMZ)-Induced Cytotoxicity against Malignant Glioma Cells In Vitro by Inhibiting Autophagy
por: Chen, Zhihua, et al.
Publicado: (2022)

miR-1297 sensitizes glioma cells to temozolomide (TMZ) treatment through targeting adrenomedullin (ADM)
por: He, Zongze, et al.
Publicado: (2022)

Conventionally fractionated stereotactic radiotherapy (CFRT) in combination with dose-dense temozolomide (TMZ) in relapsed malignant glioma: A case report
por: Qie, Shuai, et al.
Publicado: (2019)

Valproic Acid: A Promising Therapeutic Agent in Glioma Treatment
por: Han, Wei, et al.
Publicado: (2021)

TMZ-BioShuttle – a reformulated Temozolomide
por: Waldeck, Waldemar, et al.
Publicado: (2008)

Identification of miRNA signature associated with BMP2 and chemosensitivity of TMZ in glioblastoma stem-like cells
por: Guo, Xiaoyu, et al.
Publicado: (2019)

PAXX Participates in Base Excision Repair via Interacting with Pol β and Contributes to TMZ Resistance in Glioma Cells
por: Yang, Ben, et al.
Publicado: (2018)

Bortezomib inhibits growth and sensitizes glioma to temozolomide (TMZ) via down-regulating the FOXM1–Survivin axis
por: Tang, Jun-Hai, et al.
Publicado: (2019)

ATRX/EZH2 complex epigenetically regulates FADD/PARP1 axis, contributing to TMZ resistance in glioma
por: Han, Bo, et al.
Publicado: (2020)

Human Glioma Cells Therapy Using ATRA-Induced Differentiation Method to Promote the Inhibitive Effect of TMZ and CCDP
por: Li, Xinning, et al.
Publicado: (2021)

LncRNA-PVT1 was identified as a key regulator for TMZ resistance and STAT-related pathway in glioma
por: Chen, Yusheng, et al.
Publicado: (2023)

Valproic Acid Downregulates the Expression of MGMT and Sensitizes Temozolomide-Resistant Glioma Cells
por: Ryu, Chung Heon, et al.
Publicado: (2012)

Blockade of Na/H exchanger stimulates glioma tumor immunogenicity and enhances combinatorial TMZ and anti-PD-1 therapy
por: Guan, Xiudong, et al.
Publicado: (2018)

Retracted: Human Glioma Cells Therapy Using ATRA-Induced Differentiation Method to Promote the Inhibitive Effect of TMZ and CCDP
por: Healthcare Engineering, Journal of
Publicado: (2023)

High-Resolution Flow Cytometry: a Suitable Tool for Monitoring Aneuploid Prostate Cancer Cells after TMZ and TMZ-BioShuttle Treatment
por: Braun, Klaus, et al.
Publicado: (2009)

The DNA methylome of DDR genes and benefit from RT or TMZ in IDH mutant low-grade glioma treated in EORTC 22033
por: Bady, Pierre, et al.
Publicado: (2018)

The Sequence of Delta24-RGD and TMZ Administration in Malignant Glioma Affects the Role of CD8(+)T Cell Anti-tumor Activity
por: Kleijn, Anne, et al.
Publicado: (2017)

Hsa_circ_0072309 enhances autophagy and TMZ sensitivity in glioblastoma
por: Yuan, Fanen, et al.
Publicado: (2022)

Valproic Acid Inhibits Proliferation and Reduces Invasiveness in Glioma Stem Cells Through Wnt/β Catenin Signalling Activation
por: Riva, Gabriele, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_onuefgf4ip8m2sst33agbrq1ad