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Survivin knockdown induces senescence in TTF-1-expressing, KRAS-mutant lung adenocarcinomas

Survivin plays a key role in regulating the cell cycle and apoptosis, and is highly expressed in the majority of malignant tumors. However, little is known about the roles of survivin in KRAS-mutant lung adenocarcinomas. In the present study, we examined 28 KRAS-mutant lung adenocarcinoma tissues an...

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Detalles Bibliográficos
Autores principales: Sumi, Toshiyuki, Hirai, Sachie, Yamaguchi, Miki, Tanaka, Yusuke, Tada, Makoto, Yamada, Gen, Hasegawa, Tadashi, Miyagi, Yohei, Niki, Toshiro, Watanabe, Atsushi, Takahashi, Hiroki, Sakuma, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958877/
https://www.ncbi.nlm.nih.gov/pubmed/29658609
http://dx.doi.org/10.3892/ijo.2018.4365