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Tumor-derived mesenchymal-stem-cell-secreted IL-6 enhances resistance to cisplatin via the STAT3 pathway in breast cancer

Cisplatin is used for the treatment of a range of solid malignant tumors; however, with prolonged treatment durations, the sensitivity of tumor cells to the drug decreases owing to an unclear mechanism of drug resistance. The present study aimed to investigate whether breast-cancer-tissue-derived me...

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Detalles Bibliográficos
Autores principales: Xu, Huitao, Zhou, Ying, Li, Wei, Zhang, Bin, Zhang, Huanhuan, Zhao, Shaolin, Zheng, Ping, Wu, Huiyi, Yang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958889/
https://www.ncbi.nlm.nih.gov/pubmed/29844821
http://dx.doi.org/10.3892/ol.2018.8463