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Noninferiority trials
Noninferiority trials are intended to show that the effect of a new treatment is not worse than that of an active control by more than a specified margin. These trials have a number of inherent weaknesses that superiority trials do not: no internal demonstration of assay sensitivity, no single conse...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2000
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59590/ https://www.ncbi.nlm.nih.gov/pubmed/11714400 http://dx.doi.org/10.1186/cvm-1-1-019 |