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Repeated touch and needle-prick stimulation in the neonatal period increases the baseline mechanical sensitivity and postinjury hypersensitivity of adult spinal sensory neurons

Noxious stimulation at critical stages of development has long-term consequences on somatosensory processing in later life, but it is not known whether this developmental plasticity is restricted to nociceptive pathways. Here, we investigate the effect of repeated neonatal noxious or innocuous hind...

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Detalles Bibliográficos
Autores principales: van den Hoogen, Nynke J., Patijn, Jacob, Tibboel, Dick, Joosten, Bert A., Fitzgerald, Maria, Kwok, Charlie H.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959002/
https://www.ncbi.nlm.nih.gov/pubmed/29528964
http://dx.doi.org/10.1097/j.pain.0000000000001201