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Therapeutic Potential of a Novel Necrosis Inhibitor, 7-Amino-Indole, in Myocardial Ischemia–Reperfusion Injury

Opening of mitochondrial permeability transition pore and Ca(2+) overload are main contributors to myocardial ischemia–reperfusion injury, which paradoxically causes a wide variety of myocardial damage. We investigated the protective role of a novel necrosis inhibitor (NecroX-7; NecX) against myocar...

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Detalles Bibliográficos
Autores principales: Hwang, In-Chang, Kim, Ju-Young, Kim, Ji-Hyun, Lee, Joo-Eun, Seo, Ji-Yun, Lee, Jae-Won, Park, Jonghanne, Yang, Han-Mo, Kim, Soon-Ha, Cho, Hyun-Jai, Kim, Hyo-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott, Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959205/
https://www.ncbi.nlm.nih.gov/pubmed/29661840
http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09405