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Acetyl-CoA-directed gene transcription in cancer cells

Fluctuations in acetyl-coenzyme A (acetyl-CoA) levels have been previously associated with changes in global histone acetylation and gene expression. The study by Lee and colleagues (pp. 497–511) in this issue of Genes & Development demonstrates that acetyl-CoA can promote the up-regulation of c...

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Detalles Bibliográficos
Autores principales: Martínez-Reyes, Inmaculada, Chandel, Navdeep S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959230/
https://www.ncbi.nlm.nih.gov/pubmed/29692354
http://dx.doi.org/10.1101/gad.315168.118