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Transcriptional coactivator PGC-1α contains a novel CBP80-binding motif that orchestrates efficient target gene expression
Although peroxisome proliferator-activated receptor-γ (PPARγ) coactivator 1α (PGC-1α) is a well-established transcriptional coactivator for the metabolic adaptation of mammalian cells to diverse physiological stresses, the molecular mechanism by which it functions is incompletely understood. Here we...
Autores principales: | Cho, Hana, Rambout, Xavier, Gleghorn, Michael L., Nguyen, Phuong Quoc Thuc, Phipps, Christopher R., Miyoshi, Keita, Myers, Jason R., Kataoka, Naoyuki, Fasan, Rudi, Maquat, Lynne E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959238/ https://www.ncbi.nlm.nih.gov/pubmed/29654059 http://dx.doi.org/10.1101/gad.309773.117 |
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