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Most human introns are recognized via multiple and tissue-specific branchpoints

Although branchpoint recognition is an essential component of intron excision during the RNA splicing process, the branchpoint itself is frequently assumed to be a basal, rather than regulatory, sequence feature. However, this assumption has not been systematically tested due to the technical diffic...

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Detalles Bibliográficos
Autores principales: Pineda, Jose Mario Bello, Bradley, Robert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959240/
https://www.ncbi.nlm.nih.gov/pubmed/29666160
http://dx.doi.org/10.1101/gad.312058.118