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Balance between MAT2A intron detention and splicing is determined cotranscriptionally

Transcriptome analysis of human cells has revealed that intron retention controls the expression of a large number of genes with diverse cellular functions. Detained introns (DI) constitute a subgroup of transcripts with retained introns that are not exported to the cytoplasm but instead remain in t...

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Detalles Bibliográficos
Autores principales: Pendleton, Kathryn E., Park, Sung-Kyun, Hunter, Olga V., Bresson, Stefan M., Conrad, Nicholas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959247/
https://www.ncbi.nlm.nih.gov/pubmed/29563249
http://dx.doi.org/10.1261/rna.064899.117