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Identification and characterization of host proteins bound to dengue virus 3′ UTR reveal an antiviral role for quaking proteins

The four dengue viruses (DENV1-4) are rapidly reemerging infectious RNA viruses. These positive-strand viral genomes contain structured 3′ untranslated regions (UTRs) that interact with various host RNA binding proteins (RBPs). These RBPs are functionally important in viral replication, pathogenesis...

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Detalles Bibliográficos
Autores principales: Liao, Kuo-Chieh, Chuo, Vanessa, Ng, Wy Ching, Neo, Suat Peng, Pompon, Julien, Gunaratne, Jayantha, Ooi, Eng Eong, Garcia-Blanco, Mariano A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959249/
https://www.ncbi.nlm.nih.gov/pubmed/29572260
http://dx.doi.org/10.1261/rna.064006.117