Curcumin mitigates axonal injury and neuronal cell apoptosis through the PERK/Nrf2 signaling pathway following diffuse axonal injury

Diffuse axonal injury (DAI) accounts for more than 50% of all traumatic brain injury. In response to the mechanical damage associated with DAI, the abnormal proteins produced in the neurons and axons, namely, β-APP and p-tau, induce endoplasmic reticulum (ER) stress. Curcumin, a major component extr...

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Detalles Bibliográficos
Autores principales: Huang, Tingqin, Zhao, Junjie, Guo, Dan, Pang, Honggang, Zhao, Yonglin, Song, Jinning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Degeneration and Repair
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959262/
https://www.ncbi.nlm.nih.gov/pubmed/29570500
http://dx.doi.org/10.1097/WNR.0000000000001015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959262/
https://www.ncbi.nlm.nih.gov/pubmed/29570500
http://dx.doi.org/10.1097/WNR.0000000000001015

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