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Conformational ensembles of RNA oligonucleotides from integrating NMR and molecular simulations
RNA molecules are key players in numerous cellular processes and are characterized by a complex relationship between structure, dynamics, and function. Despite their apparent simplicity, RNA oligonucleotides are very flexible molecules, and understanding their internal dynamics is particularly chall...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959319/ https://www.ncbi.nlm.nih.gov/pubmed/29795785 http://dx.doi.org/10.1126/sciadv.aar8521 |