Cargando…
Conformational ensembles of RNA oligonucleotides from integrating NMR and molecular simulations
RNA molecules are key players in numerous cellular processes and are characterized by a complex relationship between structure, dynamics, and function. Despite their apparent simplicity, RNA oligonucleotides are very flexible molecules, and understanding their internal dynamics is particularly chall...
Autores principales: | Bottaro, Sandro, Bussi, Giovanni, Kennedy, Scott D., Turner, Douglas H., Lindorff-Larsen, Kresten |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959319/ https://www.ncbi.nlm.nih.gov/pubmed/29795785 http://dx.doi.org/10.1126/sciadv.aar8521 |
Ejemplares similares
-
Integrated NMR/Molecular
Dynamics Determination of
the Ensemble Conformation of a Thermodynamically Stable CUUG RNA Tetraloop
por: Oxenfarth, Andreas, et al.
Publicado: (2023) -
Integrating NMR and simulations reveals motions in the UUCG tetraloop
por: Bottaro, Sandro, et al.
Publicado: (2020) -
Conformational heterogeneity of UCAAUC RNA oligonucleotide from molecular dynamics simulations, SAXS, and NMR experiments
por: Bergonzo, Christina, et al.
Publicado: (2022) -
Structure and dynamics of a nanodisc by integrating NMR, SAXS and SANS experiments with molecular dynamics simulations
por: Bengtsen, Tone, et al.
Publicado: (2020) -
Barnaba: software for analysis of nucleic acid structures and trajectories
por: Bottaro, Sandro, et al.
Publicado: (2019)