The ciliary protein RPGRIP1L governs autophagy independently of its proteasome-regulating function at the ciliary base in mouse embryonic fibroblasts

Previously, macroautophagy/autophagy was demonstrated to be regulated inter alia by the primary cilium. Mutations in RPGRIP1L cause ciliary dysfunctions resulting in severe human diseases summarized as ciliopathies. Recently, we showed that RPGRIP1L deficiency leads to a decreased proteasomal activi...

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Detalles Bibliográficos
Autores principales: Struchtrup, Andreas, Wiegering, Antonia, Stork, Björn, Rüther, Ulrich, Gerhardt, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Brief Report - Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959336/
https://www.ncbi.nlm.nih.gov/pubmed/29372668
http://dx.doi.org/10.1080/15548627.2018.1429874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959336/
https://www.ncbi.nlm.nih.gov/pubmed/29372668
http://dx.doi.org/10.1080/15548627.2018.1429874

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