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RGC Neuroprotection Following Optic Nerve Trauma Mediated By Intranasal Delivery of Amnion Cell Secretome

PURPOSE: Intranasally delivered ST266, the biological, proteinaceous secretome of amnion-derived multipotent progenitor cells, reduces retinal ganglion cell (RGC) loss, optic nerve inflammation, and demyelination in experimental optic neuritis. This unique therapy and novel administration route deli...

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Detalles Bibliográficos
Autores principales: Grinblat, Gabriela A., Khan, Reas S., Dine, Kimberly, Wessel, Howard, Brown, Larry, Shindler, Kenneth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959511/
https://www.ncbi.nlm.nih.gov/pubmed/29847652
http://dx.doi.org/10.1167/iovs.18-24096