Combinatorial programming of human neuronal progenitors using magnetically-guided stoichiometric mRNA delivery

Identification of optimal transcription factor expression patterns to direct cellular differentiation along a desired pathway presents significant challenges. We demonstrate massively combinatorial screening of temporally-varying mRNA transcription factors to direct differentiation of neural progeni...

Descripción completa

Detalles Bibliográficos
Autores principales: Azimi, Sayyed M, Sheridan, Steven D, Ghannad-Rezaie, Mostafa, Eimon, Peter M, Yanik, Mehmet Fatih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959718/
https://www.ncbi.nlm.nih.gov/pubmed/29714688
http://dx.doi.org/10.7554/eLife.31922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959718/
https://www.ncbi.nlm.nih.gov/pubmed/29714688
http://dx.doi.org/10.7554/eLife.31922

Ejemplares similares