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G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst

Early mouse development is regulated and accompanied by dynamic changes in chromatin modifications, including G9a-mediated histone H3 lysine 9 dimethylation (H3K9me2). Previously, we provided insights into its role in post-implantation development (Zylicz et al., 2015). Here we explore the impact of...

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Detalles Bibliográficos
Autores principales: Zylicz, Jan J, Borensztein, Maud, Wong, Frederick CK, Huang, Yun, Lee, Caroline, Dietmann, Sabine, Surani, M Azim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959720/
https://www.ncbi.nlm.nih.gov/pubmed/29745895
http://dx.doi.org/10.7554/eLife.33361