Paracrine roles of cellular senescence in promoting tumourigenesis

Senescent cells activate genetic programmes that irreversibly inhibit cellular proliferation, but also endow these cells with distinctive metabolic and signalling phenotypes. Although senescence has historically been considered a protective mechanism against tumourigenesis, the activities of senesce...

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Detalles Bibliográficos
Autores principales: Gonzalez-Meljem, Jose Mario, Apps, John Richard, Fraser, Helen Christina, Martinez-Barbera, Juan Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959857/
https://www.ncbi.nlm.nih.gov/pubmed/29670296
http://dx.doi.org/10.1038/s41416-018-0066-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959857/
https://www.ncbi.nlm.nih.gov/pubmed/29670296
http://dx.doi.org/10.1038/s41416-018-0066-1

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