HIV-1 proteins dysregulate motivational processes and dopamine circuitry

Motivational alterations, such as apathy, in HIV-1+ individuals are associated with decreased performance on tasks involving frontal-subcortical circuitry. We used the HIV-1 transgenic (Tg) rat to assess effect of long-term HIV-1 protein exposure on motivated behavior using sucrose (1–30%, w/v) and...

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Detalles Bibliográficos
Autores principales: Bertrand, Sarah J., Mactutus, Charles F., Harrod, Steven B., Moran, Landhing M., Booze, Rosemarie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959859/
https://www.ncbi.nlm.nih.gov/pubmed/29777165
http://dx.doi.org/10.1038/s41598-018-25109-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959859/
https://www.ncbi.nlm.nih.gov/pubmed/29777165
http://dx.doi.org/10.1038/s41598-018-25109-0

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