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HIV-1 proteins dysregulate motivational processes and dopamine circuitry
Motivational alterations, such as apathy, in HIV-1+ individuals are associated with decreased performance on tasks involving frontal-subcortical circuitry. We used the HIV-1 transgenic (Tg) rat to assess effect of long-term HIV-1 protein exposure on motivated behavior using sucrose (1–30%, w/v) and...
Autores principales: | Bertrand, Sarah J., Mactutus, Charles F., Harrod, Steven B., Moran, Landhing M., Booze, Rosemarie M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959859/ https://www.ncbi.nlm.nih.gov/pubmed/29777165 http://dx.doi.org/10.1038/s41598-018-25109-0 |
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