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Genetic risk score of common genetic variants for impaired fasting glucose and newly diagnosed type 2 diabetes influences oxidative stress

We tested the hypothesis that the cumulative effects of common genetic variants related to elevated fasting glucose are collectively associated with oxidative stress. Using 25 single nucleotide polymorphisms (SNPs), a weighted genetic risk score (wGRS) was constructed by summing nine risk alleles ba...

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Detalles Bibliográficos
Autores principales: Kim, Minjoo, Kim, Minkyung, Huang, Limin, Jee, Sun Ha, Lee, Jong Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959868/
https://www.ncbi.nlm.nih.gov/pubmed/29777116
http://dx.doi.org/10.1038/s41598-018-26106-z