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Genetic risk score of common genetic variants for impaired fasting glucose and newly diagnosed type 2 diabetes influences oxidative stress
We tested the hypothesis that the cumulative effects of common genetic variants related to elevated fasting glucose are collectively associated with oxidative stress. Using 25 single nucleotide polymorphisms (SNPs), a weighted genetic risk score (wGRS) was constructed by summing nine risk alleles ba...
Autores principales: | Kim, Minjoo, Kim, Minkyung, Huang, Limin, Jee, Sun Ha, Lee, Jong Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959868/ https://www.ncbi.nlm.nih.gov/pubmed/29777116 http://dx.doi.org/10.1038/s41598-018-26106-z |
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