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A map of the PGC-1α- and NT-PGC-1α-regulated transcriptional network in brown adipose tissue

Transcriptional coactivator PGC-1α and its splice variant NT-PGC-1α play crucial roles in regulating cold-induced thermogenesis in brown adipose tissue (BAT). PGC-1α and NT-PGC-1α are highly induced by cold in BAT and subsequently bind to and coactivate many transcription factors to regulate express...

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Detalles Bibliográficos
Autores principales: Chang, Ji Suk, Ghosh, Sujoy, Newman, Susan, Salbaum, J. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959870/
https://www.ncbi.nlm.nih.gov/pubmed/29777200
http://dx.doi.org/10.1038/s41598-018-26244-4