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A virus-like particle-based tetravalent vaccine for hand, foot, and mouth disease elicits broad and balanced protective immunity

Hand, foot, and mouth disease (HFMD) is an infectious disease that mainly affects infants and children, causing considerable morbidity and mortality worldwide. HFMD is commonly caused by enterovirus 71 (EV71) and coxsackieviruses A16 (CVA16), A6 (CVA6), and A10 (CVA10). Formalin-inactivated EV71 vac...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Dai, Wenlong, Zhang, Chao, Zhou, Yu, Xiong, Pei, Wang, Shuxia, Ye, Xiaohua, Liu, Qingwei, Zhou, Dongming, Huang, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959873/
https://www.ncbi.nlm.nih.gov/pubmed/29777102
http://dx.doi.org/10.1038/s41426-018-0094-1