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Factor XIIIA—expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking

Lung cancer is the leading cause of cancer-related deaths worldwide, and lung squamous carcinomas (LUSC) represent about 30% of cases. Molecular aberrations in lung adenocarcinomas have allowed for effective targeted treatments, but corresponding therapeutic advances in LUSC have not materialized. H...

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Detalles Bibliográficos
Autores principales: Porrello, Alessandro, Leslie, Patrick L., Harrison, Emily B., Gorentla, Balachandra K., Kattula, Sravya, Ghosh, Subrata K., Azam, Salma H., Holtzhausen, Alisha, Chao, Yvonne L., Hayward, Michele C., Waugh, Trent A., Bae, Sanggyu, Godfrey, Virginia, Randell, Scott H., Oderup, Cecilia, Makowski, Liza, Weiss, Jared, Wilkerson, Matthew D., Hayes, D. Neil, Earp, H. Shelton, Baldwin, Albert S., Wolberg, Alisa S., Pecot, Chad V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959879/
https://www.ncbi.nlm.nih.gov/pubmed/29777108
http://dx.doi.org/10.1038/s41467-018-04355-w