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Changes in T cell effector functions over an 8-year period with TNF antagonists in patients with chronic inflammatory rheumatic diseases

The aim of the study was to clarify the effect of long-term anti-TNF therapy on T cell function in patients with rheumatologic immune-mediated inflammatory diseases (IMID). The production of IFNγ by T cells was evaluated at baseline and after 1, 2, 4, and 8 years of anti-TNF agents by means of a Qua...

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Detalles Bibliográficos
Autores principales: Sauzullo, Ilaria, Scrivo, Rossana, Sessa, Paola, Mengoni, Fabio, Vullo, Vincenzo, Valesini, Guido, Mastroianni, Claudio Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959893/
https://www.ncbi.nlm.nih.gov/pubmed/29777119
http://dx.doi.org/10.1038/s41598-018-26097-x