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Calcimimetic acts on enteric neuronal CaSR to reverse cholera toxin-induced intestinal electrolyte secretion
Treatment of acute secretory diarrheal illnesses remains a global challenge. Enterotoxins produce secretion through direct epithelial action and indirectly by activating enteric nervous system (ENS). Using a microperfused colonic crypt technique, we have previously shown that R568, a calcimimetic th...
Autores principales: | Tang, Lieqi, Jiang, Lingli, McIntyre, Megan E., Petrova, Ekaterina, Cheng, Sam X. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959902/ https://www.ncbi.nlm.nih.gov/pubmed/29777154 http://dx.doi.org/10.1038/s41598-018-26171-4 |
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