N-methyl D-aspartate receptor subtype 2B antagonist, Ro 25-6981, attenuates neuropathic pain by inhibiting postsynaptic density 95 expression

Postsynaptic density-95 (PSD-95) is a synaptic scaffolding protein that plays a crucial role in the development of neuropathic pain. However, the underlying mechanism remains unclear. To address the role of PSD-95 in N-methyl-D-aspartate receptor subtype 2B (NR2B) -mediated chronic pain, we investig...

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Detalles Bibliográficos
Autores principales: Huang, Ling-Er, Guo, Shao-Hui, Thitiseranee, Lalita, Yang, Yan, Zhou, Yan-Feng, Yao, Yong-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959906/
https://www.ncbi.nlm.nih.gov/pubmed/29777135
http://dx.doi.org/10.1038/s41598-018-26209-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959906/
https://www.ncbi.nlm.nih.gov/pubmed/29777135
http://dx.doi.org/10.1038/s41598-018-26209-7

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