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H(+)-ATPase blockade reduced renal gluconeogenesis and plasma glucose in a diabetic rat model

Vacuolar H(+)-adenosine triphosphatase (ATPase) plays important roles in urinary acid excretion, vesicular acidification to activate enzymes, and the membrane recycling of transporters in the kidney. As acidosis stimulates renal gluconeogenesis, we investigated the effect of blockade of H(+)-ATPase...

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Detalles Bibliográficos
Autores principales: Tojo, Akihiro, Hatakeyama, Saaya, Nangaku, Masaomi, Ishimitsu, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960008/
https://www.ncbi.nlm.nih.gov/pubmed/29318388
http://dx.doi.org/10.1007/s00795-017-0175-6