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H(+)-ATPase blockade reduced renal gluconeogenesis and plasma glucose in a diabetic rat model
Vacuolar H(+)-adenosine triphosphatase (ATPase) plays important roles in urinary acid excretion, vesicular acidification to activate enzymes, and the membrane recycling of transporters in the kidney. As acidosis stimulates renal gluconeogenesis, we investigated the effect of blockade of H(+)-ATPase...
Autores principales: | Tojo, Akihiro, Hatakeyama, Saaya, Nangaku, Masaomi, Ishimitsu, Toshihiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Japan
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960008/ https://www.ncbi.nlm.nih.gov/pubmed/29318388 http://dx.doi.org/10.1007/s00795-017-0175-6 |
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