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Regulation of IgE activity in inhalational tolerance via formation of IgG anti-IgE/IgE immune complexes

BACKGROUND: Allergic asthma is an inflammatory disorder of the airways that results from inappropriate production of IgE against harmless, environmental antigens. Sequestration of free IgE using humanized IgG anti-IgE is an effective therapy for asthma and other atopic disorders. However, the status...

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Detalles Bibliográficos
Autores principales: Bracken, Sonali J., Adami, Alexander J., Rafti, Ektor, Schramm, Craig M., Matson, Adam P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960149/
https://www.ncbi.nlm.nih.gov/pubmed/29796009
http://dx.doi.org/10.1186/s12948-018-0091-x