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ADAM-17 is a poor prognostic indicator for patients with hilar cholangiocarcinoma and is regulated by FoxM1

BACKGROUND: A-disintegrin and metalloproteinases (ADAMs) are members of a family of multidomain transmembrane and secreted proteins. Specific ADAMs are upregulated in human cancers and correlated with tumor progression and poor outcome, but rarely studied in human hilar cholangiocarcinoma (HC). This...

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Detalles Bibliográficos
Autores principales: Jiao, Xiaodong, Yu, Wenlong, Qian, Jianxin, Chen, Ying, Wei, Peilian, Fang, Wenzheng, Yu, Guanzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960197/
https://www.ncbi.nlm.nih.gov/pubmed/29776401
http://dx.doi.org/10.1186/s12885-018-4294-9