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A Dual-Type L2 11-88 Peptide from HPV Types 16/18 Formulated in Montanide ISA 720 Induced Strong and Balanced Th1/Th2 Immune Responses, Associated with High Titers of Broad Spectrum Cross-Reactive Antibodies in Vaccinated Mice

E. coli-derived concatenated, multitype L2-conserved epitopes of human papillomavirus (HPV) L2 protein might represent a less expensive and pan-type vaccine alternative (compared to type-specific HPV L1 virus-like particles), if stable protein expression and strong immunogenicity features could be m...

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Detalles Bibliográficos
Autores principales: Motavalli Khiavi, Farhad, Arashkia, Arash, Golkar, Majid, Nasimi, Maryam, Roohvand, Farzin, Azadmanesh, Kayhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960516/
https://www.ncbi.nlm.nih.gov/pubmed/29854852
http://dx.doi.org/10.1155/2018/9464186