EZH2 Inhibition Ameliorates Transverse Aortic Constriction-Induced Pulmonary Arterial Hypertension in Mice

BACKGROUND: EPZ005687 is a selective inhibiter of methyltransferase EZH2. In this article, we investigated the protective role and mechanism of EPZ005687 in transverse aortic constriction-induced pulmonary arterial hypertension in mice. METHODS: We assigned 15 (6–8 weeks old) male balb/c mice to 3 g...

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Detalles Bibliográficos
Autores principales: Shi, Zhan-Li, Fang, Kun, Li, Zhi-Hui, Ren, Dan-Hong, Zhang, Jia-Ying, Sun, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960552/
https://www.ncbi.nlm.nih.gov/pubmed/29854032
http://dx.doi.org/10.1155/2018/9174926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960552/
https://www.ncbi.nlm.nih.gov/pubmed/29854032
http://dx.doi.org/10.1155/2018/9174926

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