Trans-chalcone enhances insulin sensitivity through the miR-34a/SIRT1 pathway

OBJECTIVE(S): Trans-chalcone as the parent member of the chalcone series reduces circulating levels of insulin and glucose. However, the cellular mechanism of these effects is poorly understood. Sirtuin 1 (SIRT1) as a direct target of miR-34a controls homeostasis of glucose, and also improves insuli...

Descripción completa

Detalles Bibliográficos
Autores principales: Karimi-Sales, Elham, Jeddi, Sajad, Ebrahimi-Kalan, Abbas, Alipour, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960750/
https://www.ncbi.nlm.nih.gov/pubmed/29796217
http://dx.doi.org/10.22038/IJBMS.2018.24300.6063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960750/
https://www.ncbi.nlm.nih.gov/pubmed/29796217
http://dx.doi.org/10.22038/IJBMS.2018.24300.6063

Ejemplares similares