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Detection of hyper-conserved regions in hepatitis B virus X gene potentially useful for gene therapy

AIM: To detect hyper-conserved regions in the hepatitis B virus (HBV) X gene (HBX) 5’ region that could be candidates for gene therapy. METHODS: The study included 27 chronic hepatitis B treatment-naive patients in various clinical stages (from chronic infection to cirrhosis and hepatocellular carci...

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Detalles Bibliográficos
Autores principales: González, Carolina, Tabernero, David, Cortese, Maria Francesca, Gregori, Josep, Casillas, Rosario, Riveiro-Barciela, Mar, Godoy, Cristina, Sopena, Sara, Rando, Ariadna, Yll, Marçal, Lopez-Martinez, Rosa, Quer, Josep, Esteban, Rafael, Buti, Maria, Rodríguez-Frías, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960815/
https://www.ncbi.nlm.nih.gov/pubmed/29785078
http://dx.doi.org/10.3748/wjg.v24.i19.2095