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Immunocytochemical Characterization of Alzheimer’s Disease Hallmarks in APP/PS1 Transgenic Mice Treated with a New Anti-Amyloid-β Vaccine
INTRODUCTION: APP/PS1 double-transgenic mouse models of Alzheimer’s disease (AD), which overexpress mutated forms of the gene for the human amyloid precursor protein (APP) and presenilin 1 (PS1), have provided robust neuropathological hallmarks of an AD-like pattern at early ages. This study aimed t...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
University Library System, University of Pittsburgh
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960902/ https://www.ncbi.nlm.nih.gov/pubmed/29805876 http://dx.doi.org/10.5195/cajgh.2013.119 |