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Immunocytochemical Characterization of Alzheimer’s Disease Hallmarks in APP/PS1 Transgenic Mice Treated with a New Anti-Amyloid-β Vaccine

INTRODUCTION: APP/PS1 double-transgenic mouse models of Alzheimer’s disease (AD), which overexpress mutated forms of the gene for the human amyloid precursor protein (APP) and presenilin 1 (PS1), have provided robust neuropathological hallmarks of an AD-like pattern at early ages. This study aimed t...

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Detalles Bibliográficos
Autores principales: Carrera, Ivan, Etcheverria, Ignacio, Li, Yi, Fernandez-Novoa, Lucia, Lombardi, Valter, Vigo, Carmen, Palacios, Hector H., Benberin, Valery V., Cacabelos, Ramon, Aliev, Gjumrakch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: University Library System, University of Pittsburgh 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960902/
https://www.ncbi.nlm.nih.gov/pubmed/29805876
http://dx.doi.org/10.5195/cajgh.2013.119