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Role of ROS in Aβ42 Mediated Activation of Cerebral Endothelial Cells

INTRODUCTION: There is substantial evidence that the deposition of aggregated amyloid-beta peptide (Aβ) in brain parenchyma and brain vessels is the main cause of neuronal dysfunction and death in Alzheimer’s disease (AD). Aβ exhibits multiple cytotoxic effects on neurons and glial cells and causes...

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Detalles Bibliográficos
Autores principales: Tsoy, Andrey, Umbayev, Bauyrzhan, Shalakhmetova, Tamara, Askarova, Sholpan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: University Library System, University of Pittsburgh 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960947/
https://www.ncbi.nlm.nih.gov/pubmed/29805908
http://dx.doi.org/10.5195/cajgh.2014.179