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Protein composition of catalytically active U7-dependent processing complexes assembled on histone pre-mRNA containing biotin and a photo-cleavable linker

3′ end cleavage of metazoan replication-dependent histone pre-mRNAs requires the multi-subunit holo-U7 snRNP and the stem–loop binding protein (SLBP). The exact composition of the U7 snRNP and details of SLBP function in processing remain unclear. To identify components of the U7 snRNP in an unbiase...

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Detalles Bibliográficos
Autores principales: Skrajna, Aleksandra, Yang, Xiao-cui, Dadlez, Michał, Marzluff, William F, Dominski, Zbigniew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961079/
https://www.ncbi.nlm.nih.gov/pubmed/29529248
http://dx.doi.org/10.1093/nar/gky133