A putative RND-type efflux pump, H239_3064, contributes to colistin resistance through CrrB in Klebsiella pneumoniae

BACKGROUND: Colistin is one of the last-resort antibiotics used to treat carbapenem-resistant Klebsiella pneumoniae infection. Our previous studies indicated that clinical strains encoding CrrB with amino acid substitutions exhibited higher colistin resistance (MICs ≥512 mg/L) than did colistin-resi...

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Detalles Bibliográficos
Autores principales: Cheng, Yi-Hsiang, Lin, Tzu-Lung, Lin, Yi-Tsung, Wang, Jin-Town
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961088/
https://www.ncbi.nlm.nih.gov/pubmed/29506266
http://dx.doi.org/10.1093/jac/dky054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961088/
https://www.ncbi.nlm.nih.gov/pubmed/29506266
http://dx.doi.org/10.1093/jac/dky054

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