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Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells
Targeted modulation of gene expression represents a valuable approach to understand the mechanisms governing gene regulation. In a therapeutic context, it can be exploited to selectively modify the aberrant expression of a disease-causing gene or to provide the target cells with a new function. Here...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961145/ https://www.ncbi.nlm.nih.gov/pubmed/29538770 http://dx.doi.org/10.1093/nar/gky171 |