The exon–intron gene structure upstream of the initiation codon predicts translation efficiency

Introns in mRNA leaders are common in complex eukaryotes, but often overlooked. These introns are spliced out before translation, leaving exon-exon junctions in the mRNA leaders (leader EEJs). Our multi-omic approach shows that the number of leader EEJs inversely correlates with the main protein tra...

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Detalles Bibliográficos
Autores principales: Lim, Chun Shen, T. Wardell, Samuel J, Kleffmann, Torsten, Brown, Chris M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961209/
https://www.ncbi.nlm.nih.gov/pubmed/29684192
http://dx.doi.org/10.1093/nar/gky282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961209/
https://www.ncbi.nlm.nih.gov/pubmed/29684192
http://dx.doi.org/10.1093/nar/gky282

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