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Crystal structure of the novel lesion-specific endonuclease PfuEndoQ from Pyrococcus furiosus
Because base deaminations, which are promoted by high temperature, ionizing radiation, aerobic respiration and nitrosative stress, produce mutations during replication, deaminated bases must be repaired quickly to maintain genome integrity. Recently, we identified a novel lesion-specific endonucleas...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961232/ https://www.ncbi.nlm.nih.gov/pubmed/29660024 http://dx.doi.org/10.1093/nar/gky261 |