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Crystal structure of the novel lesion-specific endonuclease PfuEndoQ from Pyrococcus furiosus

Because base deaminations, which are promoted by high temperature, ionizing radiation, aerobic respiration and nitrosative stress, produce mutations during replication, deaminated bases must be repaired quickly to maintain genome integrity. Recently, we identified a novel lesion-specific endonucleas...

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Detalles Bibliográficos
Autores principales: Miyazono, Ken-ichi, Ishino, Sonoko, Makita, Naruto, Ito, Tomoko, Ishino, Yoshizumi, Tanokura, Masaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961232/
https://www.ncbi.nlm.nih.gov/pubmed/29660024
http://dx.doi.org/10.1093/nar/gky261