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IMPUTOR: Phylogenetically Aware Software for Imputation of Errors in Next-Generation Sequencing

We introduce IMPUTOR, software for phylogenetically aware imputation of missing haploid nonrecombining genomic data. Targeted for next-generation sequencing data, IMPUTOR uses the principle of parsimony to impute data marked as missing due to low coverage. Along with efficiently imputing missing var...

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Detalles Bibliográficos
Autores principales: Jobin, Matthew, Schurz, Haiko, Henn, Brenna M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961346/
https://www.ncbi.nlm.nih.gov/pubmed/29722813
http://dx.doi.org/10.1093/gbe/evy088